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Symbol Name ID |
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha MGI:1206581 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Hydrocele testis |
Ovarian cyst |
Dysgerminoma |
Ovarian papillary adenocarcinoma |
Uterine leiomyosarcoma |
| Disease(s) Associated with PIK3CA | |||||
| colorectal cancer | |||||
| Cowden syndrome 5 | |||||
| ovarian cancer |
| Mouse Phenotypes | reproductive system phenotype |
abnormal anogenital distance |
abnormal ovary morphology |
abnormal ovarian follicle number |
decreased testis weight |
increased prostate intraepithelial neoplasia incidence |
abnormal testis physiology |
delayed sexual maturation |
delayed balanopreputial separation |
reduced female fertility |
male infertility |
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| Availability | Mouse Genotype | |||||||||||
| Tg(Amhr2-Pik3ca*,-GFP)#Lzh/0 | ||||||||||||
| Pik3catm1.1Rzl/Pik3catm1.1Rzl Tg(Fabp4-cre)1Blw/0 (conditional) |
* | |||||||||||
| Pik3catm1Jjz/Pik3catm1Jjz Tg(Pbsn-cre)4Prb/0 (conditional) |
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| Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+ (conditional) | ||||||||||||
| Pik3catm1.1Waph/Pik3ca+ (conditional) | ||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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